1628 – 1629

Paulista bandeirantes raid and destroy the Jesuit missions of Guairá

In 1628-29 bandeirantes from São Paulo, led by Manuel Preto, destroy the Jesuit missions of Guairá and enslave their Guaraní. Estimates of captives range from about 5,000 to 100,000, and raids on other missions go on until 1632.